Borohydride → 5-(3-Chlorophenyl)-6-(4-chlorophenyl)-1-(1-cyclopropyl-2-hydroxyethyl)piperidin-2-one
Reaction equation
[BH4-:1].[Cl:3][c:4]1[cH:5][c:6]([CH:10]2[CH:11]([c:26]3[cH:27][cH:28][c:29]([Cl:32])[cH:30][cH:31]3)[N:12]([CH:17]([C:18](=[O:19])[O:20][CH2:21][CH3:22])[CH:23]3[CH2:24][CH2:25]3)[C:13](=[O:16])[CH2:14][CH2:15]2)[cH:7][cH:8][cH:9]1.[Li+:2]>>[Cl:3][c:4]1[cH:5][c:6]([CH:10]2[CH:11]([c:26]3[cH:27][cH:28][c:29]([Cl:32])[cH:30][cH:31]3)[N:12]([CH:17]([CH2:18][OH:19])[CH:23]3[CH2:24][CH2:25]3)[C:13](=[O:16])[CH2:14][CH2:15]2)[cH:7][cH:8][cH:9]1Participants
4
Sources & evidence
- ORD record
- ord-8e5ddf25a28f4654b9d5ca685a2e8c2b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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