HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 898114Generated: October 30, 2026
Sodium Hydroxide → Topiramate sodium trihydrate
https://huagongshe.com/reaction/898114
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Topiramate | HCID 5284627 | — |
| Solvent | Water | HCID 962 | — |
| Product | Topiramate sodium trihydrate | HCID 72941832 | — |
Reaction Steps
0.97 g (2.9 mmols) of topiramate (Cheminor Ltd.), 10 mL distilled water, and 2.8 mL 1N NaOH (2.8 mmol) were added to a glass beaker, warmed on a hotplate to 60° C. and stirred with a TEFLON-coated stir bar on a magnetic stirplate. The solid topiramate dissolved in about 25 minutes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07351695B2 |
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| Source dataset | uspto-grants-2008_04 |
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| ORD ID | ord-c638d201f2fd4705bcfdeeccb2f1ea63 |
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| Source note | uspto-grants-2008_04 |
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