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HRID898219

反应详情

EQUATION

反应方程式

HRID 898219 的结构方程式

REACTANTS

反应物

4
结构：[I-].[K+]
HCID4875

Potassium iodide

IK

结构：BrCc1ccccc1
HCID7498

alpha-Bromotoluene

C7H7Br

结构：CC[C@@H]1C(=O)Nc2cc(F)ccc2N1C(=O)c1cccc(OC)c1
HCID69221447

未命名化合物

结构：CC[C@@H]1C(=O)N(Cc2ccccc2)c2cc(F)ccc2N1C(=O)c1ccc(OC)cc1
HCID69223935

未命名化合物

PRODUCTS

生成物

1
结构：CC[C@@H]1C(=O)N(Cc2ccccc2)c2cc(F)ccc2N1C(=O)c1cccc(OC)c1
HCID69221455

未命名化合物

收率 85%

PROCEDURE

实验过程

(3R)-3-Ethyl-7-fluoro-4-(3-methoxybenzoyl)-3,4-dihydroquinoxalin-2(1H)-one (see Example 4) was treated with potassium iodide (5 eq) and benzyl bromide according to the procedure for the preparation of (3R)-1-benzyl-3-ethyl-7-fluoro-4-(4-methoxybenzoyl)-3,4-dihydroquinoxalin-2(1H)-one (see Example 2) to yield (3R)-1-benzyl-3-ethyl-7-fluoro-4-(3-methoxybenzoyl)-3,4-dihydroquinoxalin-2(1H)-one (85%).