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HRID898236

反应详情

EQUATION

反应方程式

HRID 898236 的结构方程式

REACTANTS

反应物

3
结构：CCCCBr
HCID8002

1-Bromobutane

C4H9Br

结构：CC[C@@H]1C(=O)N(C)c2cc(F)ccc2N1C(=O)c1cccc(OC)c1
HCID69221291

未命名化合物

结构：CC[C@@H]1C(=O)Nc2ccc(F)cc2N1C(=O)c1ccc(OC)cc1
HCID69223657

未命名化合物

PRODUCTS

生成物

1
结构：CCCCN1C(=O)[C@@H](CC)N(C(=O)c2ccc(OC)cc2)c2cc(F)ccc21
HCID69221484

未命名化合物

收率 76%

PROCEDURE

实验过程

(3R)-3-Ethyl-6-fluoro-4-(4-methoxybenzoyl)-3,4-dihydroquinoxalin-2(1H)-one (see Example 8) was treated with 1-bromobutane according to the procedure for the preparation of (3R)-3-ethyl-7-fluoro-4-(3-methoxybenzoyl)-1-methyl-3,4-dihydroquinoxalin-2(1H)-one (see Example 4) to yield (3R)-1-butyl-3-ethyl-6-fluoro-4-(4-methoxybenzoyl)-3,4-dihydroquinoxalin-2(1H)-one (76%). MS (ESI) m/z 385 ([M+H]+).