HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Alanine → N-(5-fluoro-2-nitrophenyl)-L-alanine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Alanine | HCID 5950 | — |
| Reactant | 2,4-Difluoronitrobenzene | HCID 67967 | — |
| Reactant | (R)-2-(4-fluoro-2-nitrophenylamino)-butyric acid | HCID 69223325 | — |
| Product | N-(5-fluoro-2-nitrophenyl)-L-alanine | HCID 69223262 | — |
Reaction Steps
2,4-Difluoronitrobenzene was treated with L-alanine according to the procedure for the preparation of (R)-2-(4-fluoro-2-nitrophenylamino)-butyric acid (see Example 1) to yield N-(5-fluoro-2-nitrophenyl)-L-alanine. MS (ESI) m/z 229 ([M+H]+); MS (ESI) m/z 227 ([M−H]−); Anal. Calcd for C9H9FN2O4: C, 47.37; H, 3.98; N, 12.28. Found: C, 47.61; H, 4.23; N, 12.39.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07351709B2 |
| Source dataset | uspto-grants-2008_04 |
| ORD ID | ord-c68e23e8b24641ff8f46a33a79a15c92 |
| Source note | uspto-grants-2008_04 |