Thionyl Chloride → HCID 69205380, compound

Participants

Reaction Steps

Thionyl chloride (7 mL) was added with stirring and cooling at 15° C. to a solution of cis-3-(benzo[1,3]dioxol-5-yl)-indan-1-ol (10 g) in dichloromethane (300 mL). The mixture was stirred at rt for 40 min. The mixture was washed twice with water, dried (MgSO4) and evaporated in vacuo to give a quantitative yield of 5-(3-chloroindan-1-yl)benzo[1,3]dioxole as an oil, which was used in the next step without further purification.

Provenance & Evidence