Ethyl Acetoacetate → HCID 13299634, compound

HRID 898503Notes

Reaction equation

[CH2:1]([CH:4]([C:10](=[O:12])[CH3:11])[C:5]([O:7][CH2:8][CH3:9])=[O:6])[CH:2]=[CH2:3].C(OCC)(=O)CC(C)=O>>[CH2:1]([CH:4]([CH:10]([OH:12])[CH3:11])[C:5]([O:7][CH2:8][CH3:9])=[O:6])[CH:2]=[CH2:3]

Participants

Reactant 2

HCID 8868Ethyl Acetoacetate

HCID 954484-Pentenoic acid, 2-acetyl-, ethyl ester

Product 1

HCID 13299634HCID 13299634, compoundYield 60%

Procedure

Ethyl 2-allyl-3-hydroxybutyrate was prepared following the procedure as described in step 1) of Preparation Example 2, except for that ethyl 2-allyl-3-oxo-butyrate was used to replace for ethyl acetoacetate. Yield 60%.

Workup

customof Preparation Example 2

Sources & evidence

ORD record: ord-fdae658a95df45c699bb4d2322dff131
Source dataset: uspto-grants-2008_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07351778B2

Reaction notes

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