HCID 2829603, compound → HCID 16090593, compound

HRID 898530Notes

Reaction equation

HRID 898530 reaction equation
Cl[C:2]1[CH:7]=[C:6]([N+:8]([O-])=O)[CH:5]=[CH:4][C:3]=1[NH:11][CH2:12][CH2:13][N:14]([CH2:17][CH3:18])[CH2:15][CH3:16]>CO.[Ni]>[CH2:17]([N:14]([CH2:15][CH3:16])[CH2:13][CH2:12][NH:11][C:3]1[CH:2]=[CH:7][C:6]([NH2:8])=[CH:5][CH:4]=1)[CH3:18]

Participants

4

Reactant 1

HCID 2829603HCID 2829603, compound

Product 1

HCID 16090593HCID 16090593, compound

Reagents, catalysts & solvents 2

HCID 935NickelCatalystHCID 887MethanolSolvent

Procedure

1.20 mg (4.416 mmol) of N′-(2-chloro-4-nitro-phenyl)-N,N-diethyl-ethane-1,2-diamine was added to a suspension of 200 mg Raney-Ni in 20 mL MeOH and the mixture was hydrogenated for 2 hours at RT under 20 psi H2 atmosphere. The catalyst was filtered off and the filtrate evaporated down i. vac.

Workup

  1. filtrationThe catalyst was filtered off
  2. customthe filtrate evaporated down i

Sources & evidence

ORD record
ord-78bd78a567bb4d6aa046a0fd899df8c7
Source dataset
uspto-grants-2008_04
Patent number
US07351719B2

Reaction notes

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