反应详情

0.86 mL (9 mmol) of phosphorus tribromide are added dropwise to a solution of 2.6 g (17.66 mmol) of (4-hydroxymethyl-phenyl)-acetonitrile in 25 mL MTBE at 0° C. After the reaction has ended the reaction mixture is combined with water at RT, the organic phase is separated off and these are extracted successively with sodium hydrogen carbonate solution and water. The organic phase is dried over magnesium sulphate and the solvent is distilled off using the rotary evaporator.

1. customthe organic phase is separated off
2. extractionthese are extracted successively with sodium hydrogen carbonate solution and water
3. dry with materialThe organic phase is dried over magnesium sulphate
4. distillationthe solvent is distilled off
5. customthe rotary evaporator