反应详情

12.6 mL aqueous NaOH (1 M) was added at RT to a suspension of 1.200 g (4.200 mmol) ethyl (E)-3-[5-(4-chloro-phenyl)-pyridin-2-yl]-acrylate (Z34a) in 50 mL EtOH and the mixture was stirred for 1 h . 12.6 mL aqueous HCl (1 M) was added at 0° C. The precipitate formed was filtered off, washed with water and dried i. vac. at 100° C.

1. customThe precipitate formed
2. filtrationwas filtered off
3. washwashed with water
4. customdried i
5. customat 100° C.