HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 5709520, compound → (e)-n-[3-Chloro-4-(3-hydroxy-propyl)-phenyl]-3-(2-chloro-4-trifluoromethyl-phenyl)-acrylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 5709520 | HCID 5709520 | — |
| Reactant | 3-(2-Chloro-4-nitro-phenyl)-propan-1-ol | HCID 68877970 | — |
| Product | (e)-n-[3-Chloro-4-(3-hydroxy-propyl)-phenyl]-3-(2-chloro-4-trifluoromethyl-phenyl)-acrylamide | HCID 68878212 | — |
Reaction Steps
Prepared analogously to Intermediate product Z32a starting from (E)-3-(2-chloro-4-trifluoromethyl-phenyl)-acrylic acid (Z37b) and 3-(2-chloro-4-nitro-phenyl)-propan-1-ol. The crude product was purified by column chromatography (silica gel, petroleum ether/EtOAc 1:1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07351719B2 |
| Source dataset | uspto-grants-2008_04 |
| ORD ID | ord-589b042339aa4505a9449eb8a2a8a466 |
| Source note | uspto-grants-2008_04 |