Hydrochloric Acid → HCID 68878219, compound

HRID 898573Notes

Reaction equation

HRID 898573 reaction equation
[OH-].[Na+].[Cl:3][C:4]1[CH:16]=[C:15]([C:17]2[O:18][CH:19]=[CH:20][CH:21]=2)[CH:14]=[CH:13][C:5]=1[O:6][CH2:7][C:8]([O:10]CC)=[O:9].CCO.Cl>O>[Cl:3][C:4]1[CH:16]=[C:15]([C:17]2[O:18][CH:19]=[CH:20][CH:21]=2)[CH:14]=[CH:13][C:5]=1[O:6][CH2:7][C:8]([OH:10])=[O:9]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 702EthanolHCID 14798Sodium HydroxideHCID 85969208HCID 85969208, compound

Product 1

HCID 68878219HCID 68878219, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

0.40 g (10.00 mmol) NaOH in 5 mL water was added to a solution of 0.280 g (2.672 mmol) ethyl (2-chloro-4-furan-2-yl-phenoxy)-acetate (130a) in 20 mL abs. EtOH and the mixture was stirred for 16 h at RT. The reaction mixture was diluted with water and acidified to pH 1 with semiconc. aqueous HCl. The precipitate was filtered off, washed with water and dried in a HV.

Workup

  1. filtrationThe precipitate was filtered off
  2. washwashed with water
  3. customdried in a HV

Sources & evidence

ORD record
ord-e1cef012dff14c5988c25b982444fb29
Source dataset
uspto-grants-2008_04
Patent number
US07351719B2

Reaction notes

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