HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 10005777, compound → n-[3-Amino-4-(2-diethylamino-ethoxy)-phenyl]-2-(2-chloro-4-trifluoromethyl-phenoxy)-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 10005777 | HCID 10005777 | — |
| Catalyst | Nickel | HCID 935 | — |
| Product | n-[3-Amino-4-(2-diethylamino-ethoxy)-phenyl]-2-(2-chloro-4-trifluoromethyl-phenoxy)-acetamide | HCID 59691580 | — |
Reaction Steps
A suspension of 330 mg (0.674 mmol) 2-(2-chloro-4-trifluoromethyl-phenoxy)-N-[4-(2-diethylamino-ethoxy)-3-nitro-phenyl]-acetamide (Example 160) and 200 mg Raney nickel was hydrogenated at RT and 3 bar. The catalyst was filtered off and the filtrate evaporated down i. vac.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07351719B2 |
| Source dataset | uspto-grants-2008_04 |
| ORD ID | ord-7f6fd77679034f6bb82333f8582a1612 |
| Source note | uspto-grants-2008_04 |