Diethylamine → n-(3-Chloro-4-diethylaminomethyl-phenyl)-2-(2-chloro-4-trifluoromethyl-phenoxy)-acetamide

HRID 898617Notes

Reaction equation

HRID 898617 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([NH:10][C:11](=[O:25])[CH2:12][O:13][C:14]2[CH:19]=[CH:18][C:17]([C:20]([F:23])([F:22])[F:21])=[CH:16][C:15]=2[Cl:24])[CH:5]=[CH:6][C:7]=1[CH2:8]Cl.[CH2:26]([NH:28][CH2:29][CH3:30])[CH3:27]>>[Cl:1][C:2]1[CH:3]=[C:4]([NH:10][C:11](=[O:25])[CH2:12][O:13][C:14]2[CH:19]=[CH:18][C:17]([C:20]([F:23])([F:21])[F:22])=[CH:16][C:15]=2[Cl:24])[CH:5]=[CH:6][C:7]=1[CH2:8][N:28]([CH2:29][CH3:30])[CH2:26][CH3:27]

Participants

3

Reactant 2

HCID 8021DiethylamineHCID 59691573HCID 59691573, compound

Product 1

HCID 59691546n-(3-Chloro-4-diethylaminomethyl-phenyl)-2-(2-chloro-4-trifluoromethyl-phenoxy)-acetamide

Procedure

Prepared analogously to Example 170 starting from N-(3-chloro-4-chloromethyl-phenyl)-2-(2-chloro-4-trifluoromethyl-phenoxy)-acetamide (Z32b) and diethylamine. The crude product was recrystallised from petroleum ether.

Workup

  1. customThe crude product was recrystallised from petroleum ether

Sources & evidence

ORD record
ord-34edbd83b2274c79bfbb44bf09bdb3ff
Source dataset
uspto-grants-2008_04
Patent number
US07351719B2

Reaction notes

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