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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 898624Generated: November 1, 2026

3-(Pyridin-2-yl)prop-2-enoic acid → HCID 59691598, compound

https://huagongshe.com/reaction/898624

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Pyridin-2-yl)prop-2-enoic acidHCID 5356626—
Reactant3-Chloro-4-(2-diethylaminoethoxy)phenylamineHCID 16791676—
ProductHCID 59691598HCID 59691598—

Reaction Steps

Prepared analogously to Example 172 starting from (E)-3-pyridin-2-yl-acrylic acid and 3-chloro-4-(2-diethylamino-ethoxy)-phenylamine (Z2b) at RT (72 h). The crude product was purified by column chromatography (silica gel, dichloromethane/MeOH/conc. aqueous ammonia 90:10:0.1) and recrystallisation from petroleum ether.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07351719B2
Source datasetuspto-grants-2008_04
ORD IDord-77b89fa1454242239e4f6e19fc6c7663
Source noteuspto-grants-2008_04