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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 898629Generated: October 25, 2026

HCID 5709520, compound → HCID 59691545, compound

https://huagongshe.com/reaction/898629

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 5709520HCID 5709520—
Reactant3-Chloro-4-(4-methyl-piperidin-1-ylmethyl)-phenylamineHCID 28721844—
ProductHCID 59691545HCID 59691545—

Reaction Steps

Prepared analogously to Example 143 starting from (E)-3-(2-chloro-4-trifluoromethyl-phenyl)-acrylic acid (Z37b) and 3-chloro-4-(4-methyl-piperidin-1-ylmethyl)-phenylamine (Z36b). The crude product was purified by column chromatography (Alox, neutral, act. II-III, petroleum ether/EtOAc 3:1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07351719B2
Source datasetuspto-grants-2008_04
ORD IDord-f15a64e1f52f4cd491e5c85ccc838b1c
Source noteuspto-grants-2008_04