反应详情

Prepared in DMF analogously to Example 143 starting from (E)-3-(2-chloro-4-trifluoromethyl-phenyl)-acrylic acid (Z37b) and 3-chloro-4-(2-diethylamino-ethyl)-phenylamine (Z44d). The reaction mixture was poured onto ice water, the precipitate was filtered off, washed with water and dried in a HV. The residue was triturated with ether, the precipitate was filtered off, washed with ether and dried in a HV.

1. additionThe reaction mixture was poured onto ice water
2. filtrationthe precipitate was filtered off
3. washwashed with water
4. customdried in a HV
5. customThe residue was triturated with ether
6. filtrationthe precipitate was filtered off
7. washwashed with ether
8. customdried in a HV