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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 898706Generated: October 30, 2026

Hydrazine hydrate (1:1) → (6-Methyl-5-propyl-pyrimidin-4-yl)-hydrazine

https://huagongshe.com/reaction/898706

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrazine hydrate (1:1)HCID 24654—
Reactant4-Chloro-6-methyl-5-propylpyrimidineHCID 22313156—
SolventEthanolHCID 702—
Product(6-Methyl-5-propyl-pyrimidin-4-yl)-hydrazineHCID 55281290—

Reaction Conditions

Temperature80 °C

Reaction Steps

A mixture of 5-propyl-4-chloro-6-methyl-pyrimidine (10 mmol) and hydrazine monohydrate (30 mmol) in ethanol (20 mL) is heated at 80° C. overnight. Solvent is removed in vacuo and the residue solid is in the next step without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07351826B2
Source datasetuspto-grants-2008_04
ORD IDord-3775f99fbe434de3b2e2bdabf0ff50f2
Source noteuspto-grants-2008_04