HRID898743

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)(C)N.CCC[C@H](N[C@@H](C)C(=O)N1[C@H](C(=O)O)C[C@@H]2CCCC[C@@H]21)C(=O)OCC

HCID441313

Perindopril erbumine

C23H43N3O5

PRODUCTS

生成物

结构：CC(C)(C)N.CCC[C@H](N[C@@H](C)C(=O)N1[C@H](C(=O)O)C[C@@H]2CCCC[C@@H]21)C(=O)OCC.O

HCID9847044

未命名化合物

收率 163.3%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID8857

Ethyl acetate

C4H8O2

PROCEDURE

实验过程

Perindopril erbumine (20 gms) was suspended in ethyl acetate (300 ml). The contents were heated to dissolve the solids and cooled to 10 EC. The resulting slurry was filtered and dried in air having a relative humidity of at least 75% to give perindopril erbumine monohydrate (17 gms).

WORKUP

后处理

temperatureThe contents were heated
dissolutionto dissolve the solids
temperaturecooled to 10 EC
filtrationThe resulting slurry was filtered
customdried in air