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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 8991Generated: October 28, 2026

5-(phenylmethoxy)-1H-indole-2-carboxylic acid → 5-Benzyloxy-3-(dimethylaminophenylmethyl)-1H-indole-2-carboxylic Acid

https://huagongshe.com/reaction/8991

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(phenylmethoxy)-1H-indole-2-carboxylic acidHCID 81146—
ReactantMethanaminium, N-methyl-N-(phenylmethylene)-, chlorideHCID 11073839—
Product5-Benzyloxy-3-(dimethylaminophenylmethyl)-1H-indole-2-carboxylic AcidHCID 10135620—

Reaction Steps

The preparation was carried out in accordance with general synthesis instructions 4 from 5-benzyloxy-1H-indole-2-carboxylic acid and benzylidene-dimethyl-ammonium chloride, which had been prepared in accordance with example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07091220B2
Source datasetuspto-grants-2006_08
ORD IDord-a26ba1aa91024edd8cc9a52003c2eac1
Source noteuspto-grants-2006_08