Ethyl 4-oxo-1-piperidinecarboxylate → HCID 69136867, compound

HRID 899266Notes

Reaction equation

HRID 899266 reaction equation
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][CH2:9][CH2:10][OH:11].[O:12]=[C:13]1[CH2:18][CH2:17][N:16]([C:19]([O:21][CH2:22][CH3:23])=[O:20])[CH2:15][CH2:14]1>>[OH:12][C:13]1([C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=2[CH2:8][CH2:9][CH2:10][OH:11])[CH2:14][CH2:15][N:16]([C:19]([O:21][CH2:22][CH3:23])=[O:20])[CH2:17][CH2:18]1

Participants

3

Procedure

The title compound was prepared according to the procedure described in step 2 of example 74 from 3-(2-bromophenyl)propan-1-ol (J. Am. Chem. Soc. 2003, 125, 3509.) and ethyl 4-oxopiperidine-1-carboxylate:

Sources & evidence

ORD record
ord-5f3e92e142c14e7c9fdcddbe37fcf446
Source dataset
uspto-grants-2008_04
Patent number
US07354925B2

Reaction notes

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