Imidazole → 1-(3-(1-Imidazolyl)-phenyl)-5 trifluoromethyl benzimidazole

HRID 90013Notes

Reaction equation

HRID 90013 reaction equation
[C:26](=[O:27])([O-:28])[O-:29].[CH3:32][N:33]1[CH2:34][CH2:35][CH2:36][C:37]1=[O:38].[I:1][c:2]1[cH:3][c:4](-[n:8]2[cH:9][n:10][c:11]3[c:12]2[cH:13][cH:14][c:15]([C:17]([F:18])([F:19])[F:20])[cH:16]3)[cH:5][cH:6][cH:7]1.[K+:30].[K+:31].[OH2:39].[nH:21]1[cH:22][n:23][cH:24][cH:25]1>>[c:2]1(-[n:21]2[cH:22][n:23][cH:24][cH:25]2)[cH:3][c:4](-[n:8]2[cH:9][n:10][c:11]3[c:12]2[cH:13][cH:14][c:15]([C:17]([F:18])([F:19])[F:20])[cH:16]3)[cH:5][cH:6][cH:7]1

Participants

7

Reactant 6

HCID 795ImidazoleHCID 813Potassium Cation2×HCID 962WaterHCID 13387N-methyl-2-pyrrolidoneHCID 19660Carbonate IonHCID 18957889HCID 18957889, compound

Product 1

HCID 194259611-(3-(1-Imidazolyl)-phenyl)-5 trifluoromethyl benzimidazole

Sources & evidence

ORD record
ord-505f1ca7683c4f46b135da222e6e6c83
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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