Dichloromethane → 2-Methyl-2-(piperazin-1-yl)propan-1-ol

HRID 90022Notes

Reaction equation

HRID 90022 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][N:11]([C:14]([CH2:15][OH:16])([CH3:17])[CH3:18])[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:26][CH2:27][Cl:28].[F:19][C:20]([F:21])([F:22])[C:23]([OH:24])=[O:25]>>[NH:8]1[CH2:9][CH2:10][N:11]([C:14]([CH2:15][OH:16])([CH3:17])[CH3:18])[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 574203451,1-Dimethylethyl 4-(2-hydroxy-1,1-dimethylethyl)-1-piperazinecarboxylate

Product 1

HCID 120525542-Methyl-2-(piperazin-1-yl)propan-1-ol

Sources & evidence

ORD record
ord-6da8ab1e26694c5aae5494bf84c98f01
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…