HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 69112412, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Lithium hydroxide, monohydrate | HCID 168937 | — |
| Reactant | HCID 69112512 | HCID 69112512 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 69112412 | HCID 69112412 | — |
Reaction Steps
2-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-3H-imidazole-4-carboxylic acid methyl ester (460 mg) and lithium hydroxide monohydrate (450 mg) in THF (3 mL) and water (1 mL) were stirred at 58° C. for 10 h. After cooling the mixture was carefully neutralized by the addition of 2 N HCl and concentrated to give crude 2-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-3H-imidazole-4-carboxylic acid. Yield: 905 mg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07358268B2 |
| Source dataset | uspto-grants-2008_04 |
| ORD ID | ord-23e01bd0d36d44a2bf192fa2d56ea35a |
| Source note | uspto-grants-2008_04 |