2,4,6-Trimethylbenzoyl chloride → HCID 22182230, compound

HRID 900401Notes

Reaction equation

HRID 900401 reaction equation
[OH:1][N:2]1[C:10]([CH3:12])([CH3:11])[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]1([CH3:14])[CH3:13].[CH3:15][C:16]1[CH:24]=[C:23]([CH3:25])[CH:22]=[C:21]([CH3:26])[C:17]=1[C:18](Cl)=[O:19]>>[CH3:15][C:16]1[CH:24]=[C:23]([CH3:25])[CH:22]=[C:21]([CH3:26])[C:17]=1[C:18]([O:1][N:2]1[C:3]([CH3:14])([CH3:13])[C:4]2[C:9](=[CH:8][CH:7]=[CH:6][CH:5]=2)[C:10]1([CH3:12])[CH3:11])=[O:19]

Participants

3

Reactant 2

HCID 970382,4,6-Trimethylbenzoyl chlorideHCID 11030629HCID 11030629, compound

Product 1

HCID 22182230HCID 22182230, compoundYield 92%

Procedure

Using this hydroxylamine compound and 2,4,6-trimethylbenzoyl chloride in a procedure otherwise similar to that for preparing the compound 101 gives a 92% yield of the compound 104 which is obtained in the form of colourless crystals; melting point: 181-183° C. (dichloromethane/methanol).

Sources & evidence

ORD record
ord-99b6ab1f611541ce9e63fe0507de084d
Source dataset
uspto-grants-2008_04
Patent number
US07358365B2

Reaction notes

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