Ethyl chloroformate → HCID 72985482, compound

HRID 900515Notes

Reaction equation

C([Cl:6])(=O)OCC.[CH2:7]([O:9][CH:10](OCC)[CH:11]1[CH2:15][CH2:14][O:13][CH:12]1OCC)[CH3:8]>>[Cl:6][CH2:14][CH2:15][C:11](=[CH:10][O:9][CH2:7][CH3:8])[CH:12]=[O:13]

Participants

Reactant 2

HCID 10928Ethyl chloroformate

HCID 115794243-(diethoxymethyl)-2-ethoxytetrahydrofuran

Product 1

HCID 72985482HCID 72985482, compoundYield 90.5%

Procedure

The operation was conducted in the same manner as in Example 8 except that the amount of ethyl chlorocarbonate was 1.3-fold mol relative to the starting material. As a result, the conversion ratio of 3-(diethoxymethyl)-2-ethoxytetrahydrofuran was 97.1%, and 4-chloro-2-ethoxymethylidenebutanal was obtained in a yield of 90.5%.

Sources & evidence

ORD record: ord-a210bf32db32414bbc84ef51d401d37f
Source dataset: uspto-grants-2008_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07358400B2

Reaction notes

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