反应详情

A mixture of 1-(2,2-dimethoxyethyl)-piperidin-2-one (1.06 g, 5.67 mmole) in 5% aqueous tetrahydrofuran (20 mL) was heated under reflux for 1 hour. The mixture was dried with anhydrous magnesium sulfate, filtered, and concentrated to give (2-oxo-piperidin-1-yl)-acetaldehyde (0.69 g) as a pale yellow oil.

1. temperaturewas heated
2. temperatureunder reflux for 1 hour
3. dry with materialThe mixture was dried with anhydrous magnesium sulfate
4. filtrationfiltered
5. concentrationconcentrated