HCID 22226540, compound → HCID 22226489, compound

Participants

Reaction Steps

(1-Isopropyl-6,7-dimethoxy-isoquinolin-4-yl)-acetic acid, characterised as the ethyl ester 1H NMR (400 MHz, CDCl3) δ 1.25 (t J 7 3H), 1.45 (d J 7 3H), 3.82 (heptet J 7 1H), 3.90 (s 2H), 3.08 (s 2H), 4.15 (q J 7 2H), 7.28 (s 1H), 7.48 (s 1H), 8.30 (s 1H). Intermediate 41: 2-(7Methoxy-1-morpholin-4-yl-isoquinolin4-yl)-propionic acid mp 225-227° C., is prepared according to the procedure for Intermediate 27.

Provenance & Evidence