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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 900745Generated: October 25, 2026

1-methyl-2,3-dihydro-1H-1,3-benzodiazol-2-one → Methyl 6-[2,3-dihydro-3-methyl-2-oxo-1H-benzimidazol-1-ylmethyl]-1,2,3,4-tetrahydro-3-methyl-1-(2-methylpropyl)-2,4-dioxo-thieno[2,3-d]pyrimidine-5-carboxylate

https://huagongshe.com/reaction/900745

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-methyl-2,3-dihydro-1H-1,3-benzodiazol-2-oneHCID 590540—
ReactantMethyl 6-bromomethyl-1-isobutyl-3-methyl-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-5-carboxylateHCID 16102871—
ProductMethyl 6-[2,3-dihydro-3-methyl-2-oxo-1H-benzimidazol-1-ylmethyl]-1,2,3,4-tetrahydro-3-methyl-1-(2-methylpropyl)-2,4-dioxo-thieno[2,3-d]pyrimidine-5-carboxylateHCID 69197857—

Reaction Steps

The subtitle compound was prepared by the method of example 1 step c) using the product of example 1 step b) and N-methylbenzimidazolone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07361660B2
Source datasetuspto-grants-2008_04
ORD IDord-bf275b09665e415c97a09eebe07ae8d6
Source noteuspto-grants-2008_04