HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Amino-5-chloro-thiophene-2-sulfonic acid bis-(2-hydroxy-ethyl)-amide → 7-Trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid {5-[bis-(2-hydroxy-ethyl)-sulfamoyl]-2-chloro-thiophen-3-yl}-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Amino-5-chloro-thiophene-2-sulfonic acid bis-(2-hydroxy-ethyl)-amide | HCID 67218487 | — |
| Reactant | 7-Trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid | HCID 86607112 | — |
| Product | 7-Trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid {5-[bis-(2-hydroxy-ethyl)-sulfamoyl]-2-chloro-thiophen-3-yl}-amide | HCID 11997465 | — |
Reaction Steps
The title compound was prepared from 7-trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C. 1) and 4-amino-5-chloro-thiophene-2-sulfonic acid bis-(2-hydroxy-ethyl)-amide (example B.5) according to general procedure II.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07361659B2 |
| Source dataset | uspto-grants-2008_04 |
| ORD ID | ord-4c8fb0007e8c4a9d999985e5a87cc992 |
| Source note | uspto-grants-2008_04 |