HRID900951

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID63946172

未命名化合物

HCID86607112

未命名化合物

PRODUCTS

产物

HCID86607124

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from 7-trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.1) and 4-methyl-5-(4-methyl-piperazine-1-sulfonyl)-thiazol-2-ylamine (example B.19) according to general procedure II. Yellow solid. MS (ISP) 634.1 [(M+H)+]; mp 273° C.

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-872b3bd14fdc49e2a1a11ee8b17becb8
来源数据集: uspto-grants-2008_04
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US07361659B2
来源说明: uspto-grants-2008_04

反应SMILES

[F:1][C:2]([F:26])([F:25])[C:3]1[N:8]2[N:9]=[CH:10][C:11]([C:12](O)=[O:13])=[C:7]2[N:6]=[C:5]([C:15]2[CH:20]=[CH:19][C:18]([C:21]([F:24])([F:23])[F:22])=[CH:17][CH:16]=2)[CH:4]=1.[CH3:27][C:28]1[N:29]=[C:30]([NH2:43])[S:31][C:32]=1[S:33]([N:36]1[CH2:41][CH2:40][N:39]([CH3:42])[CH2:38][CH2:37]1)(=[O:35])=[O:34]>>[CH3:27][C:28]1[N:29]=[C:30]([NH:43][C:12]([C:11]2[CH:10]=[N:9][N:8]3[C:3]([C:2]([F:26])([F:25])[F:1])=[CH:4][C:5]([C:15]4[CH:20]=[CH:19][C:18]([C:21]([F:24])([F:22])[F:23])=[CH:17][CH:16]=4)=[N:6][C:7]=23)=[O:13])[S:31][C:32]=1[S:33]([N:36]1[CH2:41][CH2:40][N:39]([CH3:42])[CH2:38][CH2:37]1)(=[O:35])=[O:34]