HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 63946621, compound → 7-Trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid [(RS)-5-(3-hydroxy-pyrrolidine-1-sulfonyl)-4-methyl-thiazol-2-yl]-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 63946621 | HCID 63946621 | — |
| Reactant | 7-Trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid | HCID 86607112 | — |
| Product | 7-Trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid [(RS)-5-(3-hydroxy-pyrrolidine-1-sulfonyl)-4-methyl-thiazol-2-yl]-amide | HCID 73173264 | — |
Reaction Steps
The title compound was prepared from 7-trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.1) and (RS)-1-(2-amino-4-methyl-thiazole-5-sulfonyl)-pyrrolidin-3-ol (example B.23) according to general procedure II. Light yellow solid. MS (ISP) 621.0 [(M+H)+]; mp 300° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07361659B2 |
| Source dataset | uspto-grants-2008_04 |
| ORD ID | ord-2afe7bc53f764ace9b22b5dc33d0c640 |
| Source note | uspto-grants-2008_04 |