HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Chloro-2-thiophenecarboxylic acid → {5-[(5-Chloro-thiophene-2-carbonyl)-amino]-tetrazol-2-yl}-acetic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Chloro-2-thiophenecarboxylic acid | HCID 95048 | — |
| Reactant | methyl 2-(5-amino-2H-1,2,3,4-tetrazol-2-yl)acetate | HCID 42643124 | — |
| Product | {5-[(5-Chloro-thiophene-2-carbonyl)-amino]-tetrazol-2-yl}-acetic acid methyl ester | HCID 42643127 | — |
Reaction Steps
63.2 Using general method D, (5-amino-tetrazol-2-yl)-acetic acid methyl ester was coupled with 5-chlorothiophene-2-carboxylic acid to give {5-[(5-chloro-thiophene-2-carbonyl)-amino]-tetrazol-2-yl}-acetic acid methyl ester. White solid. MS 302.0 ([M+H]+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07361672B2 |
| Source dataset | uspto-grants-2008_04 |
| ORD ID | ord-03f8dfc177d34cd9bd0b59857852425b |
| Source note | uspto-grants-2008_04 |