HRID901218

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7761

Diethyl propanedioate

C7H12O4

HCID13425103

1-Benzyl-2H-pyrido[2,3-d][1,3]oxazine-2,4(1H)-dione

C14H10N2O3

PRODUCTS

生成物

结构：CCOC(=O)c1c(O)c2cccnc2n(Cc2ccccc2)c1=O

HCID54729304

Ethyl 1-benzyl-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxylate

C18H16N2O4

PROCEDURE

实验过程

Diethyl malonate can then be reacted with the 1-benzyl-1H-pyrido[2,3-d][1,3]oxazine-2,4-dione (2) to yield the intermediate 1-benzyl-4-hydroxy-2-oxo-1,2-dihydro-[1,8]-naphthyridine-3-carboxylic acid ethyl ester (3) as shown in Scheme 3: