HCID 10180845, compound → HCID 178467707, compound

Participants

Reaction Steps

3-[4-{5-(3,4-Dihydro-2H-benzo[b][1,4]oxazin-4-yl)-5-oxopentylamino}phenyl]-2-ethoxypropanoic acid (120 mg, 1 eq, 0.28 mmol) obtained in example 11, and L-arginine (49 mg, 1 eq. 0.28 mmol) were taken in dry methanol (3 ml), and stirred at RT for 2-3 h. The solvent was removed on rotavapour followed by benzene azeotrope. The residue was dried under high vacuum pump to yield the title compound as a free filing solid (yield 100%), mp: 137-139° C.

Provenance & Evidence