HCID 10201121, compound → HCID 178467709, compound

Participants

Reaction Steps

3-[4-{3-(7-Fluoro-3,4-dihydro-2H-benzo[b][1,4]oxazin-4-yl)propylamino}phenyl]-2-ethoxypropanoic acid (120 mg, 1 eq, 0.298 mmol) obtained in example 17, and L-arginine (52 mg, 1 eq, 0.298 mmol) were taken in dry methanol (2 ml), and stirred at RT for 2-3 h. The solvent was removed on rotavapour followed by benzene azeotrope. The residue was dried under high vacuum pump to yield the title compound as a free flowing solid (yield 100%), mp: 158-160° C.

Provenance & Evidence