Magnesium Hydroxide → HCID 69205773, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of methanolic solution (2 ml) of 2-ethoxy-3-[4-{3-(3,4-dihydro-2H-benzo[b][1,4]oxazin-4-yl)propylamino}phenyl]propanoic acid (75 mg, 1 eq, 0.19 mmol) obtained in example 2 and magnesium hydroxide (5.6 mg, 0.5 eq, 0.095 mmol) was heated at 50° C. for 5 h. The resulting solution was condensed, azeotroped with benzene and then finally dried on high vacuum pump to obtain the title compound as freed flowing solid (100% yield, mp: 132-134° C.).

Provenance & Evidence