HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 69221301, compound → HCID 69220293, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 69221301 | HCID 69221301 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | HCID 69220293 | HCID 69220293 | 41% |
Reaction Steps
The ester obtained in Example 24 is dissolved in 2.5 cm3 of CH2Cl2 and 7.5 cm3 of trifluoroacetic acid. After 15 min, the solvent is evaporated by entraining it with toluene, and then the compound is crystallized from ether. 519 mg of the expected acid (41%) are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07365071B2 |
| Source dataset | uspto-grants-2008_04 |
| ORD ID | ord-41fd25aeaeb142e29e1665fa871facab |
| Source note | uspto-grants-2008_04 |