反应详情

To a stirred solution of 200 ml of boiling xylene 4.93 g ((13.9 mmol) of methyl (Z)-2-azido-3-(4-benzyloxy-3-nitrophenyl)acrylate is added in small portions. After completion of the addition the reaction mixture is refluxed until the gas formation is over (about 0.5 h), then cooled to room temperature, the precipitated product is filtered off and washed with n-hexane to yield 0.67 g (15%) of the title compound. Mp.: 184-187° C. (xylene).

1. additionAfter completion of the addition the reaction mixture
2. temperatureis refluxed until the gas formation
3. customis over (about 0.5 h)
4. filtrationthe precipitated product is filtered off
5. washwashed with n-hexane