Hydrochloric Acid → HCID 68853764, compound

Participants

Reaction Steps

In an analogous manner to Example 135, step 4, 1-[1-(3′-cyano-111′-biphenyl-4-yl)-2-piperazin-1-ylethyl]cyclohexanol dihydrochloride was prepared from tert-butyl 4-[2-(3′-cyano-1,1′-biphenyl-4-yl)-2-(1-hydroxycyclohexyl)ethyl]piperazine-1-carboxylate. MS (ES) m/z 390.3 ([M+H]+); HRMS: calcd for C25H31N3O.2.00 HCl, 461.2001; found (ESI), 390.2532.

Provenance & Evidence