HCID 68961891, compound → HCID 69117513, compound

HRID 902354Notes

Reaction equation

HRID 902354 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([O:8]C)[C:3]=1[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[Cl:16]>Br>[Cl:16][C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=1[C:3]1[C:4]([OH:8])=[CH:5][CH:6]=[CH:7][C:2]=1[Cl:1]

Participants

3

Reactant 1

HCID 68961891HCID 68961891, compound

Product 1

HCID 69117513HCID 69117513, compoundYield 89%

Reagents, catalysts & solvents 1

HCID 260Hydrogen BromideSolvent

Procedure

Treatment of 2,2′-dichloro-6-methoxybiphenyl (5.0 g, 20.9 mmol) with hydrogen bromide (33% in acetic acid, 60 mL) according to the procedure described for Example 69, Step 2 provided 4.2 g (89%) of 2′,6-dichlorobiphenyl-2-ol as a colorless oil.

Sources & evidence

ORD record
ord-aab0bcfc6b02410a9100985dc140c70e
Source dataset
uspto-grants-2008_04
Patent number
US07365095B2

Reaction notes

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