反应详情

Treatment of 4-chloro-2′-fluoro-6′-methoxy-2-methylbiphenyl (2.7 g, 10.8 mmol) with hydrogen bromide (33% in acetic acid, 50 mL) according to the procedure described for Example 69, Step 2 provided 2.2 g (86%) of 4′-chloro-6-fluoro-2′-methylbiphenyl-2-ol as a colorless oil.