HuagongsheHuagongshe Chemistry Print Report · For research reference only
Allyl bromide → 2'-Allyloxy-4-chloro-6'-fluoro-2-methylbiphenyl
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Allyl bromide | HCID 7841 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 58629987 | HCID 58629987 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | 2'-Allyloxy-4-chloro-6'-fluoro-2-methylbiphenyl | HCID 69116906 | 66.6% |
Reaction Steps
Treatment of 4′-chloro-6-fluoro-2′-methylbiphenyl-2-ol (2.7 g, 11.4 mmol) with potassium carbonate (2.4 g, 17.1 mmol) and allyl bromide (1.5 mL, 17.1 mmol) in DMSO (100 mL) according to the procedure described for Example 69, Step 3 provided 2.1 g (66%) of 2′-allyloxy-4-chloro-6′-fluoro-2-methylbiphenyl as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07365095B2 |
| Source dataset | uspto-grants-2008_04 |
| ORD ID | ord-5fadd0db07f84682989871823a5ea7ef |
| Source note | uspto-grants-2008_04 |