反应详情

Treatment of 4′-chloro-6-fluoro-2′-methylbiphenyl-2-ol (2.7 g, 11.4 mmol) with potassium carbonate (2.4 g, 17.1 mmol) and allyl bromide (1.5 mL, 17.1 mmol) in DMSO (100 mL) according to the procedure described for Example 69, Step 3 provided 2.1 g (66%) of 2′-allyloxy-4-chloro-6′-fluoro-2-methylbiphenyl as a colorless oil.