Ammonia → HCID 23122197, compound

HRID 902567Notes

Reaction equation

HRID 902567 reaction equation
[NH3:1].[CH2:2]([CH:5]1[CH2:9][CH2:8][O:7][C:6]1=[O:10])[CH:3]=[CH2:4]>COCCOC>[OH:7][CH2:8][CH2:9][CH:5]([C:6]([NH2:1])=[O:10])[CH2:2][CH:3]=[CH2:4]

Participants

4

Reactant 2

HCID 222AmmoniaHCID 125351403-(Prop-2-en-1-yl)oxolan-2-one

Product 1

HCID 23122197HCID 23122197, compound

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

In an amount of 112 mg of 3-allyldihydrofuran-2-one (WO99/36419) was dissolved in 1 ml of 1,2-dimethoxyethane, added with 1.2 ml of 28% aqueous ammonia, and stirred at room temperature for 17 hours. The reaction mixture was concentrated under reduced pressure to obtain 130 mg of 1-(2-hydroxyethyl)-3-butenecarboxamide. Physicochemical Properties of this Compound

Workup

  1. concentrationThe reaction mixture was concentrated under reduced pressure

Sources & evidence

ORD record
ord-bae905a43cfd4a12b043cc0236658394
Source dataset
uspto-grants-2008_04
Patent number
US07365174B2

Reaction notes

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