反应详情

温度

90 °C

To a stirring solution of 1-methyl-piperazine (10 ml) was added 6-chloro-2-pyridinol (1.5 g, 11.57 mmol) and the mixture was heated at 90° C. for 60 h. The reaction mixture was cooled to RT and concentrated under reduced pressure (while heating) to afford the title compound as a brown solid (66%). The crude material was used without further purification. MS (ESI) 194.2 (M+H+).

1. temperatureThe reaction mixture was cooled to RT
2. concentrationconcentrated under reduced pressure (while heating)