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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 902727Generated: October 31, 2026

2-(3-Chlorophenyl)propanoic acid → N-(3-Chloro-3-trifluoromethylbenzyl)-2-(2-chlorophenyl)propionamide

https://huagongshe.com/reaction/902727

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-Chlorophenyl)propanoic acidHCID 13109535—
ReactantN-(2-Chloro-3-trifluoromethylbenzyl)-2-(2-chlorophenyl)propionamideHCID 69254638—
ProductN-(3-Chloro-3-trifluoromethylbenzyl)-2-(2-chlorophenyl)propionamideHCID 6925469022%

Reaction Steps

The titled compound was prepared from 2-(3-Chlorophenyl)propionic acid in 22% yield in the same manner as the preparation of N-(2-Chloro-3-trifluoromethylbenzyl)-2-(2-chlorophenyl)propionamide in Example 184b. MS (ESI) 376 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07365085B2
Source datasetuspto-grants-2008_04
ORD IDord-209dd69bdce4436ab76c348c29497422
Source noteuspto-grants-2008_04