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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 902736Generated: October 29, 2026

Propionic Acid → N-(2-Chloro-3-trifluoromethylbenzyl)-2-(2-methoxyphenyl)propionamide

https://huagongshe.com/reaction/902736

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropionic AcidHCID 1032—
ReactantN-(2-Chloro-3-trifluoromethylbenzyl)-2-(2-chlorophenyl)propionamideHCID 69254638—
ProductN-(2-Chloro-3-trifluoromethylbenzyl)-2-(2-methoxyphenyl)propionamideHCID 6925112742%

Reaction Steps

The titled compound was prepared from 22-methoxyphenyl)propionic acid in 42% yield in the same manner as the preparation of N-(2-Chloro-3-trifluoromethylbenzyl)-2-(2-chlorophenyl)propionamide in Example 184b. MS (ESI) 372 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07365085B2
Source datasetuspto-grants-2008_04
ORD IDord-0975714eff3246cfbe4c077f790f32f4
Source noteuspto-grants-2008_04