HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(2-Chloro-3-trifluoromethylbenzyl)-2-(2-methoxyphenyl)propionamide → N-(2-Chloro-3-trifluoromethylbenzyl)-2-(2-methoxyphenyl)propylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(2-Chloro-3-trifluoromethylbenzyl)-2-(2-methoxyphenyl)propionamide | HCID 69251127 | — |
| Reactant | N-(2-Chloro-3-trifluoromethylbenzyl)-2-(2-chlorophenyl)propylamine | HCID 69252183 | — |
| Product | N-(2-Chloro-3-trifluoromethylbenzyl)-2-(2-methoxyphenyl)propylamine | HCID 69253869 | 28% |
Reaction Steps
The titled compound was prepared from N-(2-chloro-3-trifluoromethylbenzyl)-2-(2-methoxyphenyl)propionamide in 28% yield in the same manner as the preparation of N-(2-chloro-3-trifluoromethylbenzyl)-2-(2-chlorophenyl)propylamine in Example 184c. MS (ESI) 358 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07365085B2 |
| Source dataset | uspto-grants-2008_04 |
| ORD ID | ord-a4d8ed50645d4413a7c2468ef2ec3066 |
| Source note | uspto-grants-2008_04 |