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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 902753Generated: November 1, 2026

2-Phenylhexan-1-amine → N-(2-Phenylhexyl)-N-(2-chloro-3-trifluoromethylbenzyl)-3-(3-carboxymethylenephenoxy)propylamine, hydrochloride

https://huagongshe.com/reaction/902753

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Phenylhexan-1-amineHCID 44693—
ReactantN-(2-Phenyl-4-methylpentyl)-N-(2-chloro-3-trifluoromethylbenzyl)-3-(3-carboxymethylenephenoxy)propylamine, hydrochlorideHCID 131726851—
ProductN-(2-Phenylhexyl)-N-(2-chloro-3-trifluoromethylbenzyl)-3-(3-carboxymethylenephenoxy)propylamine, hydrochlorideHCID 131726853—

Reaction Steps

The titled compound was prepared from 2-phenylhexylamine (J. Chem. Soc. Perk. Trans. 1: Organic and Biorganic Chemistry (1976), (1), 33-8) in the same manner as the preparation of N-(2-Phenyl-4-methylpentyl)-N-(2-chloro-3-trifluoromethylbenzyl)-3-(3-carboxymethylenephenoxy)propylamine, hydrochloride, Example 189e-h. MS (ESI) 562 (MH+)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07365085B2
Source datasetuspto-grants-2008_04
ORD IDord-f38f6f00f49745b8bdff7e5068bce182
Source noteuspto-grants-2008_04